Faculty

Brian Kim, M.D.

Assistant Professor of Dermatology

 

Dr. Brian Kim received his B.S. in Chemistry from Haverford College in 2001 and his M.D. from the University of Washington School of Medicine in 2007. He trained under Dr. Stephen Katz in the Dermatology Branch of the National Cancer Institute as a Howard Hughes Medical Institute-National Institutes of Health Research Scholar from 2004-2006. In 2008, he entered his residency in dermatology at the Hospital of the University of Pennsylvania (HUP) on the physician-scientist track. He completed his residency in dermatology in 2011, his postdoctoral training in the laboratory of Dr. David Artis in 2014 and obtained a Masters in Translational Research (MTR) from the Perelman School of Medicine at the University of Pennsylvania in 2014.

 

Dr. Kim is a board-certified dermatologist and a Fellow of the American Academy of Dermatology (FAAD). He joined the Division of Dermatology at Washington University School of Medicine as an Assistant Professor of Medicine in July of 2014 and is an investigator in the Center for the Study of Itch (CSI). Clinically, he specializes in treating atopic dermatitis and chronic pruritus. His research focuses on understanding how the innate immune system regulates immunity and inflammation at the skin barrier surface.

 

Awards and Honors:

  • Howard Hughes Medical Institute Research Training Fellowship for Medical Students (2005)Alpha Omega Alpha Honor Medical Society Member (2007)1st Prize Johnson-Beerman Award, College of Physicians, Section on Dermatology (2013)American Academy of Dermatology Young Investigator Award (2014)Burroughs Wellcome Fund Career Awards for Medical Scientists Finalist (2014)
  • American Society for Clinical Investigation Young Physician-Scientist Award (2014)

 

Selected Publications:

 

Kim BS, Artis D.Group 2 Innate Lymphoid Cells in Health and Disease. Cold Spring Harbor Perspectives in Biology [Epub ahead of print], January 2015.

 

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P, Artis D. Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity. Nature [Epub ahead of print], December 2014.

 

Kim BS. Innate Lymphoid Cells in the Skin. Journal of Investigative Dermatology [Epub ahead of print] October 2014.

 

Kim BS, Wang K, Siracusa MC, Saenz SA, Brestoff JR, Monticelli LA, Noti M, Tait Wojno ED, Fung TC, Kubo M, Artis D. Basophils promote innate lymphoid cell responses in inflamed skin. Journal of Immunology (193), 3717-25, October, 2014.

 

Noti M, Kim BS, Siracusa MC, Rak GD, Kubo M, Moghaddam AE, Sattentau QA, Comeau MR, Spergel JM, Artis D. Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis. Journal of Allergy Clinical Immunology (133), 1390-9, May 2014.

 

Margolis DJ, Kim B, Apter AJ, Gupta J, Hoffstad O, Papadopoulos M, Mitra N. Thymic stromal lymphopoietin variation, filaggrin loss of function, and the persistence of atopic dermatitis. JAMA Dermatology (150), 254-9, Mar 2014.

 

Wysocka M, Kossenkov AV, Benoit BM, Troxel AB, Singer E, Schaffer A, Kim B, Dentchev T, Nagata S, Ise T, Showe LC, Rook AH. CD164 and FCRL3 are highly expressed on CD4+CD26- T cells in Sézary syndrome patients. Journal of Investigative Dermatology (134), 229-36, Jan 2014.

 

Siracusa MC, Saenz SA, Wojno ED, Kim BS, Osborne LC, Ziegler CG, Benitez AJ, Ruymann KR, Farber DL, Sleiman PM, Hakonarson H, Cianferoni A, Wang ML, Spergel JM, Comeau MR, Artis D. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation. Immunity (39), 1158-70, Dec 2013.

 

 Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. Journal of Experimental Medicine (210), 1823-37, Aug 2013.

 

Noti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D. Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis. Nature Medicine (19), 1005-13, Aug 2013.

 

Roediger G, Kyle R, Yip KH, Sumaria N, Guy TV, Kim BS, Mitchell MJ, Tay SS, Jain R, Forbes-Blom  E, Chen X, Tong PL, Bolton HA, Artis D, Paul WE, Fazekas de St. Groth B, Grimbaldeston MA, Le Gros G, Weninger W. Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nature Immunology (14), 564-73, Jun 2013.

 

Kim BS, Siracusa MC, Saenz SA, Noti M, Monticelli LA, Sonnenberg GF, Hepworth MR, Van Voorhees AS, Comeau MR, Artis D. TSLP elicits IL-33-independent innate lymphoid cell responses to promote skin inflammation. Science Translational Medicine (5), 170ra16, Jan 2013.

 

Hill DA, Siracusa MC, Abt MA, Kim BS, Kobuley D, Kubo M, Kambayashi T, LaRosa DF, Renner ED, Orange JS, Bushman FD, Artis D. Commensal bacterial-derived signals limit innate immune mechanisms of allergen-induced Th2 cell development. Nature Medicine (18), 538-46, Mar 2012.

 

Siracusa MC, Saenz SA, Hill DA, Kim BS, Headley MB, Doering TA, Wherry EJ, Jessup HK, Siegel LA, Kambayashi T, Dudek EC, Kubo M, Cianferoni A, Spergel JM, Ziegler SF, Comeau MR, Artis D. TSLP promotes interleukin-3-independent basophil hematopoiesis and type 2 inflammation. Nature (477), 229-33, Aug 2011.

 

Kim BS, Miyagawa F, Cho YH, Bennett CL, Clausen BE, Katz SI. Keratinocytes function as accessory cells for presentation of endogenous antigen expressed in the epidermis. Journal of Investigative Dermatology (129), 2805-17, Dec 2009.