The Dermatology Clinical Trials Unit is nationally recognized for developing and participating in clinical therapeutic trials. Clinical trials allow our patients to be exposed to experimental therapeutics. The trials unit is experienced in all areas of dermatologic clinical research from pre-Phase I to Phase IV. We are currently participating in a broad range of clinical trials of novel therapeutics for inflammatory and neoplastic skin disorders. The trials unit draws on the Division of Dermatology’s vast clinical experience.

Dermatology Clinical Trials Unit

Phone: (314) 273-3897                                                                                 

Email: DermTrials@email.wustl.edu

EPIC: WU IM DERM CLINICAL TRIALS POOL     

Currently Enrolling Trials

ATOPIC DERMATITIS

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

ClinicalTrials.gov Identifier: NCT06461897

CUTANEOUS T-CELL LYMPHOMA

A Confirmatory Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy of Topical HyBryte (Hypericin Sodium) and Visible-Light Activation for the Treatment of Cutaneous T-Cell Lymphoma (CTCL)

ClinicalTrials.gov Identifier: NCT06470451

HIDRADENITIS SUPPURATIVA

A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib (oral JAK-i) in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

ClinicalTrials.gov Identifier: NCT05889182

A Phase 2b, Double-Blind, Placebo-Controlled Study to Evaluate Eltrekibart (SQ; anti CXC 1/2) in Adult Participants with Moderate to Severe Hidradenitis Suppurativa   

ClinicalTrials.govIdentifier:NCT06046729

PRURIGO NODULARIS

Selective Treatment of Oral Povorcitinib in Prurigo Nodularis Study 1 (STOP-PN1) A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis

ClinicalTrials.gov Identifier: NCT06516952

SKIN CANCER

Phase IIa, Single-arm, Open-label, Clinical Trial of calcipotriene plus 5-fluorouracil Immunotherapy for Skin Cancer Prevention in Organ Transplant Recipients

ClinicalTrials.govIdentifier:NCT0569903