The Dermatology Clinical Trials Unit is nationally recognized for developing and participating in clinical therapeutic trials. Clinical trials allow our patients to be exposed to experimental therapeutics. The trials unit is experienced in all areas of dermatologic clinical research from pre-Phase I to Phase IV. We are currently participating in a broad range of clinical trials of novel therapeutics for inflammatory and neoplastic skin disorders. The trials unit draws on the Division of Dermatology’s vast clinical experience.
Dermatology Clinical Trials Unit
Mary Tabacchi, Clinical Research Coordinator
Phone: 314-362-8171 Fax: 314-362-6080
mtabacchi@wustl.edu
Nancy Bodet, Research Nurse Coordinator
Phone: 314-273-1376 Fax: 314-362-6080
nbodet@wustl.edu
Milan Anadkat, MD, Director, Clinical Trials Unit
manadkat@wustl.edu
Currently Enrolling Trials
Dr. Milan Anadkat
Placebo-Controlled Study Efficacy and Safety of BIIB059 (CD-123 antagonist) in Subjects with Active Cutaneous Lupus Erythematosus
Randomized, double-blind, multicenter study assessing short (16 weeks) and long-tem efficacy (up to 1 year), safety, and tolerability of 2 subcutaneous Secukinumab dose regimens in adult patients with moderate to severe Hidradenitis Suppurativa
Phase 1, Open-Label, Dose Escalation Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy Study of Topically Administered LUT014 (BRAF agonist) in Metastatic Colorectal Cancer Patients with EGFR Inhibitor Induced Acneiform Lesions
Dr. Becca Chibnall
PROSE Study: Prospective Observational Study of Adult Patients Receiving Dupixent for Atopic Dermatitis
Randomized, Double-Blind, Placebo-controlled study of Efficacy, Safety, and Tolerability of Serlopitant (nuerokinin inhibitor) for the treatment of Chronic Pruritus of Unknown Origin
Dr. Lynn Cornelius
PV-10 Intralesional Injection vs Systemic Chemotherapy or Intralesional Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma
Dr. Heather Jones
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate Efficacy and Safety of Lenabasum (Cannabanoid) in Dermatomyositis
Dr. Ann Martin
Randomized, Double-Blind, Vehicle-Controlled Study to Evaluate the Safety and Efficacy of BTX 1503 in Patients with Moderate to Severe Acne Vulgaris
A Multicenter, Randomized, Double-Blind, Secukinumab-controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects with Moderate to Severe Chronic Plaque Psoriasis
Dr. Amy Musiek
SOLAR: A Phase 2, Randomized, Open-Label, Parallel-Group, Active Comparator, Multicenter Study to Investigate the Efficacy and Safety of Cobomarsen (MRG-106) in Subjects with Cutaneous T-Cell Lymphoma (CTCL), Mycosis Fungoides (MF) Subtype
Phase 2A, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of PF-06823859 (IFN antagonist) in Adult Subjects with Dermatomyositis
A Double-Blind, Randomized, Vehicle Controlled, Crossover Study to Evaluate the Safety and Efficacy of Topical Naloxone Hydrochloride Lotion 0.5% for the relief of Pruritus in Patients with the Mycosis Fungoides (MF) or Sézary Syndrome (SS) Forms of Cutaneous T-Cell Lymphoma (CTCL)
Phase 3, Multicenter, Randomized, Placebo-Controlled Study to Determine the Efficacy of Topical SGX 301 and Fluorescent Bulb-Light Irradiation for the Treatment of Cutaneous T-Cell Lymphoma